HORDB

ID: hor005589
Uniprot ID: O73811
Protein name: GnRH-associated peptide 2
Gene name: gnrh2
Organism: Morone saxatilis (Striped bass) (Perca saxatilis)
Family: GnRH family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Morone (genus), Moronidae (family), Eupercaria incertae sedis, Eupercaria, Percomorphaceae, Euacanthomorphacea, Acanthomorphata, Ctenosquamata, Eurypterygia, Neoteleostei, Euteleosteomorpha (cohort), Clupeocephala, Osteoglossocephalai, Teleostei (infraclass), Neopterygii (subclass), Actinopteri (class), Actinopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0007165 signal transduction
GO CC: GO:0005576 extracellular region; GO:0005615 extracellular space

Sequence: ELDSFGTSEISEEIKLCEAGECSYLRPQRRNVLRNIILDALARELQKRK
Length: 49
Propeptide: MCVSRLVLLFGLLLCVGAQLSNAQHWSHGWYPGGKRELDSFGTSEISEEIKLCEAGECSYLRPQRRNVLRNIILDALARELQKRK
Signal peptide: MCVSRLVLLFGLLLCVGAQLSNA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

1s6w.pdb

hor005589_AF2.pdb

hor005589_ESM.pdb

Mass:	654886	Formula:	C244H410N74O78S2
Absent amino acids:	HMW	Common amino acids:	EL
pI:	6.54	Basic residues:	9
Polar residues:	12	Hydrophobic residues:	16
Hydrophobicity:	-60.82	Boman Index:	-14094
Half-Life:	1 hour	Half-Life Yeast:	30 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	99.59
Instability Index:	9698.57	Extinction Coefficient cystines:	1615
Absorbance 280nm:	33.65

PubMed ID: 9845669
Title: Multiple GnRHs present in a teleost species are encoded by separate genes: analysis of the sbGnRH and cGnRH-II genes from the striped bass, Morone saxatilis.